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Very likely not. Clay is dirt. In a large percentage of cases, no specific, identifiable cause is found. Diagnosis is based on clinical history, as there is often no specific test. Despite being hives, CSU is rarely caused by food allergies or environmental allergens.
The leading cause is believed to be autoimmune, where the immune system triggers mast cells to release histamine. It is frequently associated with Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE), rheumatoid arthritis, and type 1 diabetes.
Underlying Infections: Chronic infections, such as H. pylori bacteria, bacterial infections, and, in some cases, viral infections (e.g., hepatitis), can trigger CSU.
Chronic Illnesses: Other conditions, including malignancies (lymphoma) or vasculitis can cause chronic hives.
Certain factors can exacerbate chronic hives:
Medications: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen are common culprits.
Stress: Psychological stress and anxiety are major triggers for CSU flares.
Physical Factors: Pressure from tight clothing, heat, cold, alcohol consumption, and physical exertion.

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Clay is Plainsman M370. This is part of the aging process and can appear on any clay, depending on the conditions of storage (especially if stored in a very warm place or one exposed to sunlight). On the right this material has been fired to cone 6. The spots, although dark in the wet state, are burned away during firing. Mixing these specks back into the interior of the slug can be done quickly by wedging (diminishing worries about any allergy issues).
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